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Ownership Profile

Top Holders: Institutional Investor

Holder Shares Held % O/S Share Change Filing Date
Perceptive Advisors LLC 2,360,139 12.06 -- 3/31/22
Federated Hermes Global Investment Management Corp. 2,358,624 12.05 -- 3/31/22
BlackRock Institutional Trust Company, N.A. 1,036,982 5.30 -25,952 3/31/22
Chicago Capital, LLC 1,011,744 5.17 162,505 3/31/22
The Vanguard Group, Inc. 977,665 4.99 42,235 3/31/22
State Street Global Advisors (US) 908,728 4.64 -84,104 3/31/22
Medical Strategy GmbH 781,435 3.99 -- 12/31/21
ArrowMark Colorado Holdings, LLC 640,893 3.27 4,547 3/31/22
Decheng Capital Management III (Cayman) LLC 518,342 2.65 518,342 3/31/22
Prosight Capital 480,000 2.45 -34,082 3/31/22

Shareholder Breakdown

Shareholder Holders Value ($MM) % O/S Shares
Institution 183 535.04 92.51 18,110,202
Mutual Fund 192 184.00 32.39 6,272,349
Insider 9 7.14 1.15 224,345

Institutional Shareholder Style

Holders Value ($MM) % Inst Shares Shares
Growth 43 29.73 5.10 998,480
Aggressive Growth 3 2.68 0.43 84,727
Core Growth 32 18.46 3.20 625,828
Growth 8 8.59 1.47 287,925
Income 4 16.50 2.82 551,085
Income Value 3 16.49 2.81 550,970
Yield 1 -- -- 115
Index 27 109.29 18.74 3,669,057
Other 48 181.39 31.86 6,237,529
Broker Dealer 14 7.88 1.35 264,149
GARP 11 35.46 6.93 1,357,349
Hedge Fund 17 54.52 9.37 1,835,154
Specialty 2 0.26 0.05 10,362
VC Private Equity 3 77.48 13.16 2,576,515
Sector Specific 1 5.79 0.99 194,000
Value 29 116.71 20.09 3,932,263
Core Value 21 82.85 14.29 2,797,480
Deep Value 8 33.86 5.80 1,134,783

* Insider values reflect direct beneficial ownership.

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