Ownership Profile

Top Holders: Institutional Investor

Holder Shares Held % O/S Share Change Filing Date
Federated Hermes Global Investment Management Corp. 2,360,524 12.24 -534 9/30/21
Perceptive Advisors LLC 2,360,139 12.24 -- 9/30/21
State Street Global Advisors (US) 1,054,911 5.47 209,428 9/30/21
BlackRock Institutional Trust Company, N.A. 1,047,021 5.43 -29,198 9/30/21
The Vanguard Group, Inc. 951,406 4.94 27,009 9/30/21
Chicago Capital, LLC 849,239 4.41 29,501 12/31/21
Medical Strategy GmbH 747,535 3.88 -- 9/30/21
ArrowMark Colorado Holdings, LLC 629,577 3.27 -52,424 9/30/21
Invus Public Equities Advisors, LLC 600,000 3.11 -- 9/30/21
Rice Hall James & Associates, LLC 507,681 2.63 -2,786 9/30/21

Shareholder Breakdown

Shareholder Holders Value ($MM) % O/S Shares
Institution 171 507.54 85.60 16,502,460
Mutual Fund 189 175.79 31.12 5,992,404
Insider 9 6.93 1.29 248,826

Institutional Shareholder Style

Holders Value ($MM) % Inst Shares Shares
Growth 37 20.85 3.43 661,621
Aggressive Growth 3 2.87 0.46 88,079
Core Growth 29 15.96 2.64 508,638
Growth 5 2.02 0.34 64,904
Income 4 9.84 1.64 315,423
Income Value 2 9.84 1.64 315,243
Yield 2 0.01 -- 180
Index 27 116.71 19.45 3,749,323
Other 50 194.13 32.24 6,215,436
Broker Dealer 19 12.63 2.10 404,967
GARP 11 42.58 7.08 1,364,876
Hedge Fund 16 57.30 9.53 1,836,689
Specialty 1 0.75 0.17 32,389
VC Private Equity 3 80.85 13.36 2,576,515
Value 30 136.59 22.75 4,384,990
Core Value 23 104.22 17.34 3,343,698
Deep Value 7 32.37 5.40 1,041,292

* Insider values reflect direct beneficial ownership.

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