Ownership Profile

Shareholder Breakdown

Shareholder Holders Value ($MM) % O/S Shares
Institution 114 368.52 95.12 11,385,455
Mutual Fund 126 85.32 23.78 2,846,979
Insider 3 1.43 0.38 45,448

Institutional Shareholder Rotation

Shareholder Holders Value Chg ($MM) % O/S Share Change
Buyers 47 18.69 4.72 565,560
Sellers 44 -28.20 6.87 -822,672
Net -- -9.51 2.15 -257,112

Institutional Shareholder Concentration

Value ($MM) % O/S Shares
Total Inst. 368.52 95.12 11,385,455
Top 10 Inst. 246.30 63.71 7,625,629
Top 20 Inst. 313.40 80.98 9,693,529
Top 50 Inst. 360.56 93.04 11,136,879

Institutional Shareholder Style

Holders Value ($MM) % Inst Shares Shares
Growth 20 13.74 3.46 414,641
Aggressive Growth 1 4.12 1.04 125,000
Core Growth 15 8.94 2.25 268,887
Growth 4 0.68 0.17 20,754
Income 2 1.54 0.39 46,607
Income Value 1 0.84 0.21 25,426
Yield 1 0.70 0.18 21,181
Index 18 36.62 9.29 1,112,090
Momentum 1 0.43 0.11 13,100
Other 34 200.15 50.95 6,099,052
Broker Dealer 8 0.70 0.18 21,188
GARP 7 28.81 7.62 912,657
Hedge Fund 15 89.58 22.71 2,718,217
Specialty 1 1.15 0.36 43,401
VC/Private Equi 3 79.91 20.08 2,403,589
Value 17 44.37 11.27 1,348,972
Core Value 12 20.60 5.24 627,785
Deep Value 5 23.77 6.02 721,187

Top Holders: Institutional Investor

Holder Shares Held % O/S Share Change Filing Date
Perceptive Advisors LLC 1,704,330 14.24 -- 9/30/18
Phase4 Ventures Limited 1,065,447 8.90 -100,000 1/30/18
Satter Muneer A 832,000 6.95 -- 4/1/18
TPG Capital, L.P. 716,381 5.98 -- 9/30/18
TVM Capital GmbH 621,761 5.19 -- 4/1/18
Federated Global Investment Management Corp. 586,146 4.90 -- 9/30/18
ArrowMark Colorado Holdings, LLC 556,067 4.65 42,818 9/30/18
BlackRock Institutional Trust Company, N.A. 535,356 4.47 58,204 9/30/18
AstraZeneca Plc 508,141 4.25 -500,000 12/1/17
Invus Public Equities Advisors, LLC 500,000 4.18 -- 9/30/18

* Insider values reflect direct beneficial ownership.

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