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Ownership Profile

Ownership Profile

Shareholder Breakdown

Shareholder Holders Value ($MM) % O/S Shares
Institution 43 143.53 72.68 6,468,061
Mutual Fund 20 4.18 1.97 175,244
Insider -- -- -- --

Institutional Shareholder Rotation

Shareholder Holders Value Chg ($MM) % O/S Share Change
Buyers 18 19.11 9.03 803,477
Sellers 12 -1.75 0.94 -83,462
Net -- 17.35 8.09 720,015

Institutional Shareholder Concentration

Value ($MM) % O/S Shares
Total Inst. 143.53 72.68 6,468,061
Top 10 Inst. 131.31 66.33 5,902,644
Top 20 Inst. 142.08 71.96 6,403,670
Top 50 Inst. 143.53 72.68 6,468,061

Institutional Shareholder Style

Holders Value ($MM) % Inst Shares Shares
Growth 5 0.11 0.05 4,134
Core Growth 4 0.11 0.05 4,085
Growth 1 -- -- 49
Index 4 1.53 0.82 73,015
Momentum 1 0.32 0.17 15,200
Other 17 105.70 53.63 4,773,124
Broker Dealer 2 0.01 -- 248
GARP 3 4.80 2.56 228,130
Hedge Fund 9 47.64 22.25 1,980,442
VC/Private Equi 3 53.26 28.81 2,564,304
Value 6 1.75 0.91 81,424
Core Value 4 1.70 0.89 79,039
Deep Value 2 0.05 0.03 2,385

Top Holders: Institutional Investor

Holder Shares Held % O/S Share Change Filing Date
Perceptive Advisors LLC 1,320,000 14.83 475,000 12/1/17
Phase4 Ventures Limited 1,165,447 13.10 -- 4/1/17
Satter Muneer A 830,000 9.33 830,000 5/24/17
TPG Capital, L.P. 777,096 8.73 -- 9/30/17
TVM Capital GmbH 621,761 6.99 -- 4/1/17
AstraZeneca Plc 508,141 5.71 -500,000 12/1/17
Baker Bros. Advisors LP 200,000 2.25 -- 9/30/17
Point72 Asset Management, L.P. 186,640 2.10 171,098 9/30/17
Sectoral Asset Management Inc. 158,027 1.78 -30,685 9/30/17
Renaissance Technologies LLC 135,532 1.52 -9,900 9/30/17

* Insider values reflect direct beneficial ownership.

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