Ownership Profile

Shareholder Breakdown

Shareholder Holders Value ($MM) % O/S Shares
Institution 106 383.50 93.63 11,207,132
Mutual Fund 99 96.49 23.52 2,815,358
Insider 3 1.43 0.38 45,448

Institutional Shareholder Rotation

Shareholder Holders Value Chg ($MM) % O/S Share Change
Buyers 70 58.35 13.77 1,647,917
Sellers 30 -24.19 5.74 -686,750
Net -- 34.16 8.03 961,167

Institutional Shareholder Concentration

Value ($MM) % O/S Shares
Total Inst. 383.50 93.63 11,207,132
Top 10 Inst. 259.74 64.12 7,675,187
Top 20 Inst. 329.53 80.70 9,660,327
Top 50 Inst. 375.57 91.74 10,981,671

Institutional Shareholder Style

Holders Value ($MM) % Inst Shares Shares
Growth 18 11.41 2.70 323,179
Aggressive Growth 1 4.44 1.04 125,000
Core Growth 13 6.23 1.48 177,408
Growth 4 0.74 0.17 20,771
Income 2 1.50 0.35 42,357
Income Value 1 0.89 0.21 25,100
Yield 1 0.61 0.14 17,257
Index 18 35.99 8.47 1,014,067
Momentum 1 0.48 0.11 13,400
Other 33 212.36 51.01 6,105,270
Broker Dealer 9 1.08 0.25 30,363
GARP 6 35.10 8.42 1,007,925
Hedge Fund 14 93.75 22.07 2,641,269
Specialty 1 0.70 0.18 22,124
VC/Private Equi 3 81.73 20.08 2,403,589
Value 13 45.86 10.81 1,294,100
Core Value 9 21.94 5.18 620,041
Deep Value 4 23.93 5.63 674,059

Top Holders: Institutional Investor

Holder Shares Held % O/S Share Change Filing Date
Perceptive Advisors LLC 1,704,330 14.24 -- 6/30/18
Phase4 Ventures Limited 1,065,447 8.90 -100,000 1/30/18
Satter Muneer A 832,000 6.95 -- 4/1/18
TPG Capital, L.P. 716,381 5.98 -60,715 6/30/18
Fidelity Management & Research Company 627,732 5.24 -- 6/30/18
TVM Capital GmbH 621,761 5.19 -- 4/1/18
Federated Global Investment Management Corp. 586,146 4.90 276,251 6/30/18
ArrowMark Colorado Holdings, LLC 513,249 4.29 107,897 6/30/18
AstraZeneca Plc 508,141 4.25 -500,000 12/1/17
Invus Public Equities Advisors, LLC 500,000 4.18 -47,841 6/30/18

* Insider values reflect direct beneficial ownership.

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